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hh_psc_alpha – Hodgkin-Huxley neuron model

Description

hh_psc_alpha is an implementation of a spiking neuron using the Hodgkin-Huxley formalism.

1. Postsynaptic currents Incoming spike events induce a postsynaptic change of current modelled by an alpha function. The alpha function is normalized such that an event of weight 1.0 results in a peak current of 1 pA.

2. Spike Detection Spike detection is done by a combined threshold-and-local-maximum search: if there is a local maximum above a certain threshold of the membrane potential, it is considered a spike.

Parameters

The following parameters can be set in the status dictionary.

V_m

mV

Membrane potential

E_L

mV

Leak reversal potential

C_m

pF

Capacity of the membrane

g_L

nS

Leak conductance

tau_ex

ms

Rise time of the excitatory synaptic alpha function

tau_in

ms

Rise time of the inhibitory synaptic alpha function

E_Na

mV

Sodium reversal potential

g_Na

nS

Sodium peak conductance

E_K

mV

Potassium reversal potential

g_K

nS

Potassium peak conductance

Act_m

real

Activation variable m

Inact_h

real

Inactivation variable h

Act_n

real

Activation variable n

I_e

pA

External input current

Problems/Todo

  • better spike detection

  • initial wavelet/spike at simulation onset

References

1

Gerstner W, Kistler W (2002). Spiking neuron models: Single neurons, populations, plasticity. New York: Cambridge University Press

2

Dayan P, Abbott LF (2001). Theoretical neuroscience: Computational and mathematical modeling of neural systems. Cambridge, MA: MIT Press. https://pure.mpg.de/pubman/faces/ViewItemOverviewPage.jsp?itemId=item_3006127>

3

Hodgkin AL and Huxley A F (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of Physiology 117. DOI: https://doi.org/10.1113/jphysiol.1952.sp004764

Sends

SpikeEvent

Receives

SpikeEvent, CurrentEvent, DataLoggingRequest